Michal (Miki) Rahat

2024

Bronchiectasis with Chronic Rhinosinusitis Is Associated with Eosinophilic Airway Inflammation and Is Distinct from Asthma

Shteinberg, M., Chalmers, J. D., Narayana, J. K., Dicker, A. J., Rahat, M. A., Simanovitch, E., Bidgood, L., Cohen, S., Stein, N., Abo-Hilu, N., Abbott, J., Avital, S., Fireman-Klein, E., Richardson, H., Muhammad, E., Jrbashyan, J., Schneer, S., Nasrallah, N., Eisenberg, I. & Chotirmall, S. H. & 1 others, Adir, Y., 1 May 2024, In: Annals of the American Thoracic Society. 21, 5, p. 748-758 11 p.

Research output: Contribution to journal › Article › peer-review

EMMPRIN promotes spheroid organization and metastatic formation: comparison between monolayers and spheroids of CT26 colon carcinoma cells

Feigelman, G., Simanovich, E., Brockmeyer, P. & Rahat, M. A., 25 Apr 2024, In: Frontiers in Immunology. 15, p. 1374088 1374088.

Research output: Contribution to journal › Article › peer-review

Open Access

Glucose Promotes EMMPRIN/CD147 and the Secretion of Pro-Angiogenic Factors in a Co-Culture System of Endothelial Cells and Monocytes

Ghandour, F., Kassem, S., Simanovich, E. & Rahat, M. A., 22 Mar 2024, In: Biomedicines. 12, 4, 706.

Research output: Contribution to journal › Article › peer-review

Open Access

Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S

Rahat, M. M., Sabtan, H., Simanovich, E., Haddad, A., Gazitt, T., Feld, J., Slobodin, G., Kibari, A., Elias, M., Zisman, D. & Rahat, M. A., 22 Jan 2024, In: Frontiers in Immunology. 15, p. 1319939 1319939.

Research output: Contribution to journal › Article › peer-review

Open Access

Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S

Zisman, D., Sabtan, H., Rahat, M. M., Simanovich, E., Haddad, A., Gazitt, T., Feld, J., Slobodin, G., Kibari, A., Elias, M. & Rahat, M. A., 2 Jul 2024, In: International Journal of Molecular Sciences. 25, 13, 7267.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Combined Biomarker System Predicts Prognosis in Patients with Metastatic Oral Squamous Cell Carcinoma

Khromov, T., Fischer, L., Leha, A., Bremmer, F., Fischer, A., Schliephake, H., Rahat, M. A. & Brockmeyer, P., 10 Oct 2023, In: Cancers. 15, 20, 4924.

Research output: Contribution to journal › Article › peer-review

Open Access

Cuproptosis-related molecular subtypes direct T cell exhaustion phenotypes and therapeutic strategies for patients with lung adenocarcinoma

Zhu, Y. P., Deng, H. T., Wang, X., Rahat, M. A., Sun, S. & Zhang, Q. Z., 11 Apr 2023, In: Frontiers in Pharmacology. 14, p. 1146468 1146468.

Research output: Contribution to journal › Article › peer-review

Open Access

Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages

Feigelman, G., Simanovich, E., Brockmeyer, P. & Rahat, M. A., Mar 2023, In: Biomedicines. 11, 3, 768.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors

Hijaze, N., Ledersnaider, M., Simanovich, E., Kassem, S. & Rahat, M. A., Aug 2021, In: Journal of Leukocyte Biology. 110, 2, p. 343-356 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Prognostic factor identification by screening changes in differentially expressed genes in oral squamous cell carcinoma

Schminke, B., Shomroni, O., Salinas, G., Bremmer, F., Kauffmann, P., Schliephake, H., Oyelami, F., Rahat, M. A. & Brockmeyer, P., 5 May 2021, In: Oral Diseases. 29, 1, p. 116-127 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147

Zisman, D., Safieh, M., Simanovich, E., Feld, J., Kinarty, A., Zisman, L., Gazitt, T., Haddad, A., Elias, M., Rosner, I., Kaly, L. & Rahat, M. A., 15 Dec 2021, In: Frontiers in Immunology. 12, 739592.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis

Rahat, M. A., Safieh, M., Simanovich, E., Pasand, E., Gazitt, T., Haddad, A., Elias, M. & Zisman, D., 14 Oct 2020, In: Arthritis Research and Therapy. 22, 1, p. 240 240.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Effects of tocilizumab, an anti-interleukin-6 receptor antibody, on serum lipid and adipokine levels in patients with rheumatoid arthritis

Hoffman, E., Rahat, M. A., Feld, J., Elias, M., Rosner, I., Kaly, L., Lavie, I., Gazitt, T. & Zisman, D., 2 Sep 2019, In: International Journal of Molecular Sciences. 20, 18, 4633.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Active Vaccination With EMMPRIN-Derived Multiple Antigenic Peptide (161-MAP) Reduces Angiogenesis in a Dextran Sodium Sulfate (DSS)-Induced Colitis Model

Simanovich, E., Brod, V. & Rahat, M., 10 Dec 2018, In: Frontiers in Immunology. 9, 2919.

Research output: Contribution to journal › Article › peer-review

Open Access

Function of miR-146a-5p in tumor cells as a regulatory switch between cell death and angiogenesis: Macrophage therapy revisited

Simanovich, E., Brod, V., Rahat, M. M. & Rahat, M. A., 5 Jan 2018, In: Frontiers in Immunology. 8, JAN, 1931.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased Prevalence of Metabolic Syndrome and Adipocytokine Levels in a Psoriatic Arthritis Cohort

Feld, J., Nissan, S., Eder, L., Rahat, M. A., Elias, M., Rimar, D., Laor, A., Bitterman, H. & Zisman, D., 1 Sep 2018, In: Journal of Clinical Rheumatology. 24, 6, p. 302-307 6 p.

Research output: Contribution to journal › Article › peer-review

Modulation of anti-tumor immunity by the brain's reward system

Ben-Shaanan, T. L., Schiller, M., Azulay-Debby, H., Korin, B., Boshnak, N., Koren, T., Krot, M., Shakya, J., Rahat, M., Hakim, F. & Rolls, A., 1 Dec 2018, In: Nature Communications. 9, 1, 2723.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Inhibition of tumor growth and metastasis by EMMPRIN multiple antigenic peptide (MAP) vaccination is mediated by immune modulation

Simanovich, E., Brod, V., Rahat, M. M., Drazdov, E., Walter, M., Shakya, J. & Rahat, M. A., 2 Jan 2017, In: OncoImmunology. 6, 1, e1261778.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

An epitope-specific novel anti-EMMPRIN polyclonal antibody inhibits tumor progression

Walter, M., Simanovich, E., Brod, V., Lahat, N., Bitterman, H. & Rahat, M. A., 1 Feb 2016, In: OncoImmunology. 5, 2, e1078056.

Research output: Contribution to journal › Article › peer-review

Open Access

Oxygen mitigates the inflammatory response in a model of hemorrhage and zymosan-induced inflammation

Rahat, M. A., Brod, V., Amit-Cohen, B. C., Henig, O., Younis, S. & Bitterman, H., 28 Jan 2016, In: Shock. 45, 2, p. 198-208 11 p.

Research output: Contribution to journal › Article › peer-review

Role of microRNA in regulation of myeloma-related angiogenesis and survival

Preis, M. & Rahat, M. A., 1 Jan 2016, In: World Journal of Hematology. 5, 2, p. 51-60

Research output: Contribution to journal › Article › peer-review

2013

Tumor cell-macrophage interactions increase angiogenesis through secretion of EMMPRIN

Amit-Cohen, B. C., Rahat, M. M. & Rahat, M., 2013, In: Frontiers in Physiology. 4 JUL, 178.

Research output: Contribution to journal › Article › peer-review

Open Access

2012

Changes in the monocytic subsets CD14^dimCD16⁺ and CD14⁺⁺CD16^- in chronic systolic heart failure patients

Amir, O., Spivak, I., Lavi, I. & Rahat, M. A., 2012, In: Mediators of Inflammation. 89, 3, p. 201-209 616384.

Research output: Contribution to journal › Article › peer-review

Open Access

Dose-related effects of hyperoxia on the lung inflammatory response in septic rats

Waisman, D., Brod, V., Rahat, M. A., Amit-Cohen, B. C., Lahat, N., Rimar, D., Menn-Josephy, H., David, M., Lavon, O., Cavari, Y. & Bitterman, H., Jan 2012, In: Shock. 37, 1, p. 95-102 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2011

Hypoxia increases membranal and secreted HLA-DR in endothelial cells, rendering them T-cell activators

Lahat, N., Bitterman, H., Weiss-Cerem, L. & Rahat, M. A., Oct 2011, In: Transplant International. 24, 10, p. 1018-1026 9 p.

Research output: Contribution to journal › Article › peer-review

MMP expression in leaking filtering blebs and tears after glaucoma filtering surgery

Mathalone, N., Marmor, S., Rahat, M. A., Lahat, N., Oron, Y. & Geyer, O., Jul 2011, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 249, 7, p. 1047-1055 9 p.

Research output: Contribution to journal › Article › peer-review

Reduced TIMP-2 in hypoxia enhances angiogenesis

Lahat, N., Bitterman, H., Engelmayer-Goren, M., Rosenzweig, D., Weiss-Cerem, L. & Rahat, M. A., Mar 2011, In: American Journal of Physiology - Cell Physiology. 300, 3, p. C557-C566

Research output: Contribution to journal › Article › peer-review

2010

Loss of inducible nitric oxide synthase expression in the mouse renal cell carcinoma cell line RENCA is mediated by MicroRNA miR-146a

Perske, C., Lahat, N., Levin, S. S., Bitterman, H., Hemmerlein, B. & Rahat, M. A., Oct 2010, In: American Journal of Pathology. 177, 4, p. 2046-2054 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2009

The effect of 100% oxygen on intestinal preservation and recovery following ischemia-reperfusion injury in rats

Sukhotnik, I., Brod, V., Lurie, M., Rahat, M. A., Shnizer, S., Lahat, N., Mogilner, J. G. & Bitterman, H., Mar 2009, In: Critical Care Medicine. 37, 3, p. 1054-1061 8 p.

Research output: Contribution to journal › Article › peer-review

The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis

Carmi, Y., Voronov, E., Dotan, S., Lahat, N., Rahat, M. A., Fogel, M., Huszar, M., White, M. R., Dinarello, C. A. & Apte, R. N., 1 Oct 2009, In: Journal of Immunology. 183, 7, p. 4705-4714 10 p.

Research output: Contribution to journal › Article › peer-review

2008

Hypoxia enhances lysosomal TNF-α degradation in mouse peritoneal macrophages

Lahat, N., Rahat, M. A., Kinarty, A., Weiss-Cerem, L., Pinchevski, S. & Bitterman, H., Jul 2008, In: American Journal of Physiology - Cell Physiology. 295, 1, p. C2-C12

Research output: Contribution to journal › Article › peer-review

Subclinical atherosclerosis in psoriatic arthritis: A case-control study

Eder, L., Zisman, D., Barzilai, M., Laor, A., Rahat, M., Rozenbaum, M., Bitterman, H., Feld, J., Rimar, D. & Rosner, I., May 2008, In: Journal of Rheumatology. 35, 5, p. 877-882 6 p.

Research output: Contribution to journal › Article › peer-review

2007

Native and fragmented fibronectin oppositely modulate monocyte secretion of MMP-9

Marom, B., Rahat, M. A., Lahat, N., Weiss-Cerem, L., Kinarty, A. & Bitterman, H., 1 Jun 2007, In: Journal of Leukocyte Biology. 81, 6, p. 1466-1476 11 p.

Research output: Contribution to journal › Article › peer-review

The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia

Mathalone, N., Lahat, N., Rahat, M. A., Bahar-Shany, K., Oron, Y. & Geyer, O., May 2007, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 245, 5, p. 725-732 8 p.

Research output: Contribution to journal › Article › peer-review

2004

Cytokeratin-17 as a potential marker for squamous cell carcinoma of the larynx

Raanan, C.-K., Rahat, M., Madah, W., Greenberg, E., Sabo, E. & Elmalah, I., Oct 2004, In: Annals of Otology, Rhinology and Laryngology. 113, 10, p. 821-827 7 p.

Research output: Contribution to journal › Article › peer-review

2003

Hypoxia inactivates inducible nitric oxide synthase in mouse macrophages by disrupting its interaction with α-actinin 4

Daniliuc, S., Bitterman, H., Rahat, M. A., Kinarty, A., Rosenzweig, D. & Nitza, L., 15 Sep 2003, In: Journal of Immunology. 171, 6, p. 3225-3232 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Hypoxia reduces CD80 expression on monocytes but enhances their LPS-stimulated TNF-α secretion

Lahat, N., Rahat, M. A., Ballan, M., Weiss-Cerem, L., Engelmayer, M. & Bitterman, H., Aug 2003, In: Journal of Leukocyte Biology. 74, 2, p. 197-205 9 p.

Research output: Contribution to journal › Article › peer-review

2002

Detection of cytokeratins in normal and malignant laryngeal epithelia by means of reverse transcriptase-polymerase chain reaction

Cohen-Kerem, R., Lahat, N., Elmalah, I., Greenberg, E., Resnick, M. B., Doweck, I. & Rahat, M. A., 2002, In: Annals of Otology, Rhinology and Laryngology. 111, 2, p. 149-154 6 p.

Research output: Contribution to journal › Article › peer-review

2001

Divergent effects of ischemia/reperfusion and nitric oxide donor on TNFα mRNA accumulation in rat organs

Rahat, M. A., Lahat, N., Smollar, J., Brod, V., Kinarty, A. & Bitterman, H., Apr 2001, In: Shock. 15, 4, p. 312-317 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased binding of IFN regulating factor 1 mediates the synergistic induction of CIITA by IFN-γ and tumor necrosis factor-α in human thyroid carcinoma cells

Rahat, M. A., Chernichovski, I. & Lahat, N., 2001, In: International Immunology. 13, 11, p. 1423-1432 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Telomerase activity and cytokeratin 20 as markers for the detection and followup of transitional cell carcinoma: An unfulfilled promise

Cassel, A., Rahat, M. A., Lahat, N., Lindenfeld, N., Mecz, Y. & Stein, A., 2001, In: Journal of Urology. 166, 3, p. 841-844 4 p.

Research output: Contribution to journal › Article › peer-review

Transforming growth factor-β suppresses tumor necrosis factor α-induced matrix metalloproteinase-9 expression in monocytes

Vaday, G. G., Schor, H., Rahat, M. A., Lahat, N. & Lider, O., 2001, In: Journal of Leukocyte Biology. 69, 4, p. 613-621 9 p.

Research output: Contribution to journal › Article › peer-review

2000

Fibronectin-bound TNF-α stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis

Vaday, G. G., Hershkoviz, R., Rahat, M. A., Lahat, N., Cahalon, L. & Lider, O., 2000, In: Journal of Leukocyte Biology. 68, 5, p. 737-747 11 p.

Research output: Contribution to journal › Article › peer-review

Telomerase activity in HPV-associated vulvar vestibulitis

Bornstein, J., Lahat, N., Sharon, A., Gazawi, H., Abramovici, H. & Rahat, M. A., 2000, In: The Journal of reproductive medicine. 45, 8, p. 643-648 6 p.

Research output: Contribution to journal › Article › peer-review

1999

Abdominal surgery reduces the ability of rat spleen cells to synthesize and secrete active tumour necrosis factor-alpha (TNF-α) by a multilevel regulation

Lahat, N., Rahat, M. A., Brod, V., Cohen, S., Weber, G., Kinarty, A. & Bitterman, H., 1999, In: Clinical and Experimental Immunology. 115, 1, p. 19-25 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Increased telomerase activity and decreased telomere length in genital condylomata acuminata

Rahat, M. A., Lahat, N., Sharon, A., Gazawi, H., Abramovici, H. & Bornstein, J., 1999, In: International Journal of STD and AIDS. 10, 11, p. 699-702 4 p.

Research output: Contribution to journal › Article › peer-review

Telomerase activity in patients with transitional cell carcinoma: A preliminary study

Rahat, M. A., Lahat, N., Gazawi, H., Resnick, M. B., Sova, Y., Ben-Ari, G., Cohen, M. & Stein, A., 15 Feb 1999, In: Cancer. 85, 4, p. 919-924 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1998

Regulation of HLA-DR and costimulatory B7 molecules in human thyroid carcinoma cells: Differential binding of transcription factors to the HLA- DRα promoter

Lahat, N., Rahat, M. A., Sadeh, O., Kinarty, A. & Kraiem, Z., 1998, In: Thyroid. 8, 5, p. 361-369 9 p.

Research output: Contribution to journal › Article › peer-review

1996

Polymerase chain reaction search for viral etiology of vulvar vestibulitis syndrome

Bornstein, J., Shapiro, S., Rahat, M., Goldshmid, N., Goldik, Z., Abramovici, H. & Lahat, N., 1996, In: American Journal of Obstetrics and Gynecology. 175, 1, p. 139-144 6 p.

Research output: Contribution to journal › Article › peer-review

1995

Etiology of cervical cancer: Current concepts

Bornstein, J., Rahat, M. & Abramovici, H., Feb 1995, In: Obstetrical and Gynecological Survey. 50, 2, p. 146-154 9 p.

Research output: Contribution to journal › Article › peer-review

Michal (Miki) Rahat

Research output

Search results