TY - JOUR
T1 - A novel method for hydrogel nanostructuring
AU - Yom-Tov, Ortal
AU - Frisman, Ilya
AU - Seliktar, Dror
AU - Bianco-Peled, Havazelet
N1 - Funding Information:
This research was supported by the Singapore National Research Foundation under CREATE programme: The Regenerative Medicine Initiative in Cardiac Restoration Therapy (NRF-Technion).
PY - 2014/3
Y1 - 2014/3
N2 - Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic® F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.
AB - Nanostructured hydrogels tailor-made for specific applications are new grounds for the creation of novel soft materials. The current research presents a new method for hydrogel nanostructuring involving the incorporation of Pluronic® F127 micelles mixed with acrylated blockcopolymer molecules, which enable the attachment of these micelles to the hydrogel matrix through their endgroups. This design impacts the hydrogel nanostructure as well as its swelling and mechanical properties. Small Angle X-ray Scattering (SAXS) and Cryogenic Transmission Electron Microscopy (cryo-TEM) revealed that photochemical crosslinking of the hydrogel caused immobilization of the nanostructured micelles. Mechanical and weight gain experiments demonstrated a significant impact of these nanostructures on the hydrogel's elastic modulus as well as the transient and equilibrium weight gain ability of the material.
KW - Hydrogel
KW - Nanostructuring
KW - SAXS
KW - Structure
UR - http://www.scopus.com/inward/record.url?scp=84893039565&partnerID=8YFLogxK
U2 - 10.1016/j.eurpolymj.2014.01.004
DO - 10.1016/j.eurpolymj.2014.01.004
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AN - SCOPUS:84893039565
SN - 0014-3057
VL - 52
SP - 137
EP - 145
JO - European Polymer Journal
JF - European Polymer Journal
IS - 1
ER -