Entorhinal Cortex: Use it or lose it

Ohad Rechnitz; Dori Derdikman

doi:10.7554/eLife.85437

Entorhinal Cortex: Use it or lose it

Research output: Contribution to journal › Editorial

Abstract

Blocking the activity of neurons in a region of the brain involved in memory leads to cell death, which could help explain the spatiotemporal disorientation observed in Alzheimer's disease.

Original language	English
Number of pages	4
Journal	eLife
Volume	12
DOIs	https://doi.org/10.7554/eLife.85437 https://doi.org/10.7554/eLife.85437
State	Published - 24 Jan 2023

Keywords

activity-dependent competition
Alzheimer's disease
chemogenetic silencing
circuit plasticity
entorhinal cortex
mouse
neuroscience
selective vulnerability

ASJC Scopus subject areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

Access to Document

Cite this

@article{8062f77157c743d7aa0cd2ce48fb9409,

title = "Entorhinal Cortex: Use it or lose it",

abstract = "Blocking the activity of neurons in a region of the brain involved in memory leads to cell death, which could help explain the spatiotemporal disorientation observed in Alzheimer's disease.",

keywords = "activity-dependent competition, Alzheimer's disease, chemogenetic silencing, circuit plasticity, entorhinal cortex, mouse, neuroscience, selective vulnerability",

author = "Ohad Rechnitz and Dori Derdikman",

note = "{\textcopyright} 2023, Rechnitz and Derdikman.",

year = "2023",

month = jan,

day = "24",

doi = "10.7554/eLife.85437",

language = "אנגלית",

volume = "12",

}

TY - JOUR

T1 - Entorhinal Cortex

T2 - Use it or lose it

AU - Rechnitz, Ohad

AU - Derdikman, Dori

PY - 2023/1/24

Y1 - 2023/1/24

N2 - Blocking the activity of neurons in a region of the brain involved in memory leads to cell death, which could help explain the spatiotemporal disorientation observed in Alzheimer's disease.

AB - Blocking the activity of neurons in a region of the brain involved in memory leads to cell death, which could help explain the spatiotemporal disorientation observed in Alzheimer's disease.

KW - activity-dependent competition

KW - Alzheimer's disease

KW - chemogenetic silencing

KW - circuit plasticity

KW - entorhinal cortex

KW - mouse

KW - neuroscience

KW - selective vulnerability

UR - http://www.scopus.com/inward/record.url?scp=85147047843&partnerID=8YFLogxK

U2 - 10.7554/eLife.85437

DO - 10.7554/eLife.85437

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.editorial???

C2 - 36692286

SN - 2050-084X

VL - 12

JO - eLife

JF - eLife

ER -

Entorhinal Cortex: Use it or lose it

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this