TY - JOUR
T1 - Müller cells separate between wavelengths to improve day vision with minimal effect upon night vision
AU - Labin, Amichai M.
AU - Safuri, Shadi K.
AU - Ribak, Erez N.
AU - Perlman, Ido
N1 - Funding Information:
We thank S. Shoham, R. Heinrich, N. Meitav, S.G. Lipson and E. Zemel for discussions. This research was partially supported by grants from the Israel Science Foundation, one to E.N.R. and another to I.P.
PY - 2014/7/8
Y1 - 2014/7/8
N2 - Vision starts with the absorption of light by the retinal photoreceptors-cones and rods. However, due to the 'inverted' structure of the retina, the incident light must propagate through reflecting and scattering cellular layers before reaching the photoreceptors. It has been recently suggested that Müller cells function as optical fibres in the retina, transferring light illuminating the retinal surface onto the cone photoreceptors. Here we show that Müller cells are wavelength-dependent wave-guides, concentrating the green-red part of the visible spectrum onto cones and allowing the blue-purple part to leak onto nearby rods. This phenomenon is observed in the isolated retina and explained by a computational model, for the guinea pig and the human parafoveal retina. Therefore, light propagation by Müller cells through the retina can be considered as an integral part of the first step in the visual process, increasing photon absorption by cones while minimally affecting rod-mediated vision.
AB - Vision starts with the absorption of light by the retinal photoreceptors-cones and rods. However, due to the 'inverted' structure of the retina, the incident light must propagate through reflecting and scattering cellular layers before reaching the photoreceptors. It has been recently suggested that Müller cells function as optical fibres in the retina, transferring light illuminating the retinal surface onto the cone photoreceptors. Here we show that Müller cells are wavelength-dependent wave-guides, concentrating the green-red part of the visible spectrum onto cones and allowing the blue-purple part to leak onto nearby rods. This phenomenon is observed in the isolated retina and explained by a computational model, for the guinea pig and the human parafoveal retina. Therefore, light propagation by Müller cells through the retina can be considered as an integral part of the first step in the visual process, increasing photon absorption by cones while minimally affecting rod-mediated vision.
UR - http://www.scopus.com/inward/record.url?scp=84903975794&partnerID=8YFLogxK
U2 - 10.1038/ncomms5319
DO - 10.1038/ncomms5319
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C2 - 25003477
AN - SCOPUS:84903975794
SN - 2041-1723
VL - 5
JO - Nature Communications
JF - Nature Communications
M1 - 4319
ER -
