TY - JOUR
T1 - Measurement of speed of sound dispersion in soft tissues using a double frequency continuous wave method
AU - Levy, Yoav
AU - Agnon, Yehuda
AU - Azhari, Haim
N1 - Funding Information:
We are grateful for funding provided by the Galil Center For Telemedicine and Medical Informatics and by the Technion V.P.R. Research Funds, Eliyahu Pen Research Fund, Dent Charitable Trust, Japan Technion Society and the Montréal Biomedical Fund. Finally, we thank Mr. Aharon Alfasi for his extremely valuable technical support.
PY - 2006/7
Y1 - 2006/7
N2 - We introduce a method for measuring the speed of sound dispersion. It combines a short pulse transmission followed by a long burst comprised of two frequencies, one being double that of the other. The method allows the determination of the speed of sound dispersion using a single transmission. To validate the method, the dispersion was first measured in plastic samples and then in in vitro soft tissues samples. The results obtained for Perspex samples are in excellent agreement with values reported in the literature. The dispersion index in soft tissues ranged for a bovine heart from 0.63 ± 0.24 (m/s · MHz) at 1.5 MHz to 0.27 ± 0.05 (m/s · MHz) at 4.5 MHz and for a turkey breast from 1.3 ± 0.28 (m/s · MHz) at 1.75 MHz to 0.73 ± 0.1 (m/s · MHz) at 3.8 MHz. The significant difference in the speed of sound dispersion index between the studied materials indicates that dispersion may be used as a new index for soft tissue characterization by ultrasound. (E-mail: [email protected]).
AB - We introduce a method for measuring the speed of sound dispersion. It combines a short pulse transmission followed by a long burst comprised of two frequencies, one being double that of the other. The method allows the determination of the speed of sound dispersion using a single transmission. To validate the method, the dispersion was first measured in plastic samples and then in in vitro soft tissues samples. The results obtained for Perspex samples are in excellent agreement with values reported in the literature. The dispersion index in soft tissues ranged for a bovine heart from 0.63 ± 0.24 (m/s · MHz) at 1.5 MHz to 0.27 ± 0.05 (m/s · MHz) at 4.5 MHz and for a turkey breast from 1.3 ± 0.28 (m/s · MHz) at 1.75 MHz to 0.73 ± 0.1 (m/s · MHz) at 3.8 MHz. The significant difference in the speed of sound dispersion index between the studied materials indicates that dispersion may be used as a new index for soft tissue characterization by ultrasound. (E-mail: [email protected]).
KW - Dispersion
KW - Speed of sound
KW - Tissue characterization
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=33745622371&partnerID=8YFLogxK
U2 - 10.1016/j.ultrasmedbio.2006.04.003
DO - 10.1016/j.ultrasmedbio.2006.04.003
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AN - SCOPUS:33745622371
SN - 0301-5629
VL - 32
SP - 1065
EP - 1071
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 7
ER -