TY - JOUR
T1 - Sentinel node detection in an animal study
T2 - Evaluation of a new portable gamma camera
AU - Kopelman, Doron
AU - Blevis, Ira
AU - Iosilevsky, Galina
AU - Hatoum, Ossama A.
AU - Zaretzki, Assaf
AU - Shofti, Rona
AU - Salmon, Tal
AU - Israel, Ora
AU - Hashmonai, Moshe
PY - 2007/5
Y1 - 2007/5
N2 - We tested the capacity of a newly developed portable gamma camera to precisely locate sentinel nodes by injecting a radiotracer. Two sets of experiments were performed on eight pigs under general anesthesia. 99mTc-Nanocolloid and dye complex was injected in the submuscular layer of the small bowel in the first set and subcutaneously in the knee region in the second set of experiments. Image acquisition of the sentinel nodes was performed with the Camera placed at various angles. A mosaic of images was obtained encompassing the injection sites, lymphatic pathways, and sentinel lymph nodes. Three-dimensional visualizations were obtained, allowing the precise location and complete excision of these nodes. The use of the portable gamma camera allowed the rapid visualization of the lymphatic pathways leading from the injection sites to the sentinel nodes and precise location of these nodes. The Camera was also useful to verify the complete removal of the labeled target tissues.
AB - We tested the capacity of a newly developed portable gamma camera to precisely locate sentinel nodes by injecting a radiotracer. Two sets of experiments were performed on eight pigs under general anesthesia. 99mTc-Nanocolloid and dye complex was injected in the submuscular layer of the small bowel in the first set and subcutaneously in the knee region in the second set of experiments. Image acquisition of the sentinel nodes was performed with the Camera placed at various angles. A mosaic of images was obtained encompassing the injection sites, lymphatic pathways, and sentinel lymph nodes. Three-dimensional visualizations were obtained, allowing the precise location and complete excision of these nodes. The use of the portable gamma camera allowed the rapid visualization of the lymphatic pathways leading from the injection sites to the sentinel nodes and precise location of these nodes. The Camera was also useful to verify the complete removal of the labeled target tissues.
KW - Intraoperative gamma camera
KW - Radio-guided surgery
KW - Sentinel node
UR - http://www.scopus.com/inward/record.url?scp=35648938004&partnerID=8YFLogxK
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AN - SCOPUS:35648938004
SN - 0020-8868
VL - 92
SP - 161
EP - 166
JO - International Surgery
JF - International Surgery
IS - 3
ER -