MODIFIED AMINOGLYCOSIDE COMPOUNDS AND USES THEREOF IN DISABLING BACTERIAL RIBOSOME

Timor Baasov (Inventor), Boris Smolkin (Inventor), Alina Khononov (Inventor), Michal Shavit Kishkober (Inventor), Valery Belakhov (Inventor)

Research output: Patent

Abstract

Modified aminoglycoside compounds represented by Formula I as defined and described in the specification are provided. The modified aminoglycosides feature a diamine-containing functional moiety at one or more of positions 3′, 4′ and 6′. Uses of the modified aminoglycosides as antimicrobial (e.g., antibacterial) agents, and in treating medical conditions associated with microorganisms, are also provided.

Original languageAmerican English
Patent numberUS2021275557
IPCA61K 31/ 7036 A I
Priority date20/05/21
StatePublished - 9 Sep 2021

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