Modified fluoroquinolones and uses thereof

Timor Baasov; Valery Belakhov; Moshe Nissim Goldmeier

Modified fluoroquinolones and uses thereof

Timor Baasov (Inventor), Valery Belakhov (Inventor), Moshe Nissim Goldmeier (Inventor)

Chemistry

Research output: Patent

Abstract

Modified quinolones (e.g., fluoroquinolones) featuring a quinolone (e.g., fluoroquinolone) skeleton having conjugated thereto, via selected linkers, a metal chelating moiety, and metal complexes thereof, are provided. Uses of the compounds and complexes in treating medical conditions associated with pathogenic microorganism are also provided.

Original language	American English
Patent number	WO2022153310
State	Published - 21 Jul 2022

Keywords

transition metal fluoroquinolone derivative complex preparation DNA binding cleavage
antibacterial transition metal fluoroquinolone derivative complex

Cite this

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title = "Modified fluoroquinolones and uses thereof",

abstract = "Modified quinolones (e.g., fluoroquinolones) featuring a quinolone (e.g., fluoroquinolone) skeleton having conjugated thereto, via selected linkers, a metal chelating moiety, and metal complexes thereof, are provided. Uses of the compounds and complexes in treating medical conditions associated with pathogenic microorganism are also provided.",

keywords = "transition metal fluoroquinolone derivative complex preparation DNA binding cleavage, antibacterial transition metal fluoroquinolone derivative complex",

author = "Timor Baasov and Valery Belakhov and Goldmeier, {Moshe Nissim}",

year = "2022",

month = jul,

day = "21",

language = "American English",

type = "Patent",

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TY - PAT

T1 - Modified fluoroquinolones and uses thereof

AU - Baasov, Timor

AU - Belakhov, Valery

AU - Goldmeier, Moshe Nissim

PY - 2022/7/21

Y1 - 2022/7/21

N2 - Modified quinolones (e.g., fluoroquinolones) featuring a quinolone (e.g., fluoroquinolone) skeleton having conjugated thereto, via selected linkers, a metal chelating moiety, and metal complexes thereof, are provided. Uses of the compounds and complexes in treating medical conditions associated with pathogenic microorganism are also provided.

AB - Modified quinolones (e.g., fluoroquinolones) featuring a quinolone (e.g., fluoroquinolone) skeleton having conjugated thereto, via selected linkers, a metal chelating moiety, and metal complexes thereof, are provided. Uses of the compounds and complexes in treating medical conditions associated with pathogenic microorganism are also provided.

KW - transition metal fluoroquinolone derivative complex preparation DNA binding cleavage

KW - antibacterial transition metal fluoroquinolone derivative complex

M3 - Patent

M1 - WO2022153310

ER -

Modified fluoroquinolones and uses thereof

Abstract

Keywords

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